Optimal Number of Pleural Biopsies During Pleuroscopy
- Conditions
- Pleural Diseases
- Registration Number
- NCT06897878
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Brief Summary
A single-center, non-randomized, prospective observational, pilot study designed to determine what is the optimal number of pleural biopsies to take during pleuroscopy.
- Detailed Description
After enrollment, participants will undergo pleural biopsies via pleuroscopy. Specimens will be divided into three aliquots (1-3, 4-6, 7-10), which will be sent to pathology. A designated pathologist will evaluate the specimens in each aliquot to determine the number of biopsies required to reach a diagnosis and to obtain sufficient material for biomarker testing (when needed), and determine whether analysis of further aliquots is needed.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 50
- Consecutive patients who require pleuroscopies will be enrolled to the study.
- Age ≥ 18
- Inability to provide informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of pleural biopsies to reach a diagnosis At week 2 after pleuroscopy The number of pleural biopsies needed to reach a diagnosis.
- Secondary Outcome Measures
Name Time Method Number of pleural biopsies required for comprehensive biomarker testing. At week 4 after pleuroscopy The number of biopsies required to obtain sufficient material for comprehensive biomarker testing.
Number of complications At week 4 after pleuroscopy Number of complications related to the biopsy.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
Trial Locations
- Locations (1)
Mount Sinai Hospital
🇺🇸New York, New York, United States