Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes
- Conditions
- Dentine Hypersensitivity
- Interventions
- Other: Nano-HydroxyapatiteOther: Stannous FluorideOther: 8% Arginine & Calcium CarbonateOther: Sodium Monofluorophosphate
- Registration Number
- NCT06197555
- Lead Sponsor
- Altinbas University
- Brief Summary
Dentin hypersensitivity is a common problem in society. Untreated hypersensitivity affects the patient's quality of life, complicates plaque control and increases the risk of caries and periodontal disease. This study aimed to evaluate the clinical efficacy of desensitizing toothpastes containing sodium fluoride, stannous fluoride, nano-hydroxyapatite, 8% arginine and calcium carbonate.
Fourty eight patients with at least two teeth with positive responses to air and mechanical stimulus were included in the study and were divided into four groups. Sodium fluoride (Colgate®, Cavity Protection) in group A, stannous fluoride (Oral B® Gum Calm \& Sensitivity) in group B, nano-hydroxyapatite (ApaCare®) in group C and 8% arginine and calcium carbonate combination in group D (Colgate® Sensitive Pro- ReliefTM) were used by the patients continuously for 16 weeks. Dentin hypersensitivity, by using VAS and Shiff scores and periodontal parameters were evaluated at baseline, 2nd week, 4th week and last 16th week.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
- Dentin hypersensitivity complaints
- Systemically healthy
- Not during pregnancy & lactation
- No sensitivity treatment in the last 6 months
- Forty-eight patients with positive response to VAS and Schiff tests were included.
People who have;
- Any systemic disease
- Take regular medication for any other reason
- Undergone periodontal surgery within the last 6 months,
- History of allergy to toothpaste materials,
- Active caries, restoration and/or bridge on the sensitive tooth,
- Orthodontic appliances,
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group C (Nano-Hydroxyapatite) Nano-Hydroxyapatite Dentifrice containing Nano-Hydroxyapatite, daily homecare usage ApaCare® Group B (Stannous Fluoride) Stannous Fluoride Dentifrice containing Stannous Fluoride, daily homecare usage Oral B®, Gum Calm \& Sensitivity Group D (8% Arginine & Calcium Carbonate) 8% Arginine & Calcium Carbonate Dentifrice containing 8% Arginine \& Calcium Carbonate, daily homecare usage Colgate®, Sensitive Pro-Relief Group A (Sodium Monofluorophosphate) Sodium Monofluorophosphate Dentifrice containing Sodium Monofluorophosphate, daily homecare usage Colgate®, Cavity Protection
- Primary Outcome Measures
Name Time Method Hypersensitivity Reduction Baseline, 2nd week, 4th week, 16th week The Schiff Scale examiner covers the adjacent teeth on either side of the patient's hypersensitive tooth with his/her fingers. Air from the tip of the dental unit's air-water sprayer is applied to the cervical region of the hypersensitive tooth at a distance of approximately 1 cm for 1 second. The degree of hypersensitivity is scored according to the Schiff cold air sensitivity scale. Scoring :
Score 0: The individual does not respond to the stimulus. Score 1: The individual responds to the stimulus but does not request its termination. Score 2: The individual responds to the stimulus and requests its termination or moves to avoid the stimulus. Score 3: The individual responds to the stimulus, finds the stimulus painful and requests its termination. The pain persists for a few seconds after the stimulus is terminated.
- Secondary Outcome Measures
Name Time Method Clinical Periodontal Measurements Baseline, 16th week Bleeding score (%)
Trial Locations
- Locations (1)
Altinbas University
🇹🇷Istanbul, Turkey