Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- Hypersensitivity Reduction
研究概览
简要总结
Dentin hypersensitivity is a common problem in society. Untreated hypersensitivity affects the patient's quality of life, complicates plaque control and increases the risk of caries and periodontal disease. This study aimed to evaluate the clinical efficacy of desensitizing toothpastes containing sodium fluoride, stannous fluoride, nano-hydroxyapatite, 8% arginine and calcium carbonate.
Fourty eight patients with at least two teeth with positive responses to air and mechanical stimulus were included in the study and were divided into four groups. Sodium fluoride (Colgate®, Cavity Protection) in group A, stannous fluoride (Oral B® Gum Calm & Sensitivity) in group B, nano-hydroxyapatite (ApaCare®) in group C and 8% arginine and calcium carbonate combination in group D (Colgate® Sensitive Pro- ReliefTM) were used by the patients continuously for 16 weeks. Dentin hypersensitivity, by using VAS and Shiff scores and periodontal parameters were evaluated at baseline, 2nd week, 4th week and last 16th week.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Dentin hypersensitivity complaints
- •Systemically healthy
- •Not during pregnancy & lactation
- •No sensitivity treatment in the last 6 months
- •Forty-eight patients with positive response to VAS and Schiff tests were included.
排除标准
- •People who have;
- •Any systemic disease
- •Take regular medication for any other reason
- •Undergone periodontal surgery within the last 6 months,
- •History of allergy to toothpaste materials,
- •Active caries, restoration and/or bridge on the sensitive tooth,
- •Orthodontic appliances,
结局指标
主要结局
Hypersensitivity Reduction
时间窗: Baseline, 2nd week, 4th week, 16th week
Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be').
次要结局
- Clinical Periodontal Measurements(Baseline, 16th week)
研究者
Sevdenur GÜNENÇ
Dentist
Altinbas University