Tranexamic Acid for the Prevention of Postpartum Haemorrhage
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- blood loss
研究概览
简要总结
Use of Tranexamic Acid for prevention of Postpartum hemorrhage in high risk patients: Randomized Control Trial
详细描述
This study aims to assess the efficacy of administration of Tranexamic Acid in preventing Postpartum haemorrhage & reducing intraoperative and postoperative blood loss in high risk women for Postpartum Hemorrhage undergoing caesarean section. Studying its benefit to transfusion-sparing and hysterectomy-sparing. & reduction of hemorrhage-related mortality when Postpartum hemorrhage is expected.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women at high risk for postpartum hemorrhage after cesarean section
排除标准
- •women who are not at high risk for postpartum hemorrhage , or attending for normal vaginal delivery.
研究组 & 干预措施
Study
Tranexamic acid 1 gm (100 mg/ml) slowly intravenous infusion during delivery ( administered over 10 minutes at 1 ml/minute) .
干预措施: Tranexamic acid injection (Drug)
结局指标
主要结局
blood loss
时间窗: immediately after deliver
Estimation of blood loss
次要结局
- blood pressure(immediately after delivery)
- pulse(immediately after delivery)
- temperature(immeditely after delivery)
研究者
Dr. Abou Bakr Mohamed El Nashaar
professor
Benha University