Prevention of Postpartum Haemorrhage

Not Applicable

• Conditions: Post Partum Hemorrhage
• Interventions: Drug: Tranexamic acid injection

• Registration Number: NCT04463966
• Lead Sponsor: Benha University

Brief Summary

Use of Tranexamic Acid for prevention of Postpartum hemorrhage in high risk patients: Randomized Control Trial

Detailed Description

This study aims to assess the efficacy of administration of Tranexamic Acid in preventing Postpartum haemorrhage \& reducing intraoperative and postoperative blood loss in high risk women for Postpartum Hemorrhage undergoing caesarean section. Studying its benefit to transfusion-sparing and hysterectomy-sparing. \& reduction of hemorrhage-related mortality when Postpartum hemorrhage is expected.

Study Timeline

• Study Start: 2020-04-30
• Study First Submitted: 2020-04-30
• Status Verified: 2020-07
• Study First Submitted QC: 2020-07-08
• Last Update Submitted: 2020-07-08
• Study First Posted: 2020-07-09
• Last Update Posted: 2020-07-09
• Primary Completion: 2021-04
• Study Completion: 2021-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• Women at high risk for postpartum hemorrhage after cesarean section

Exclusion Criteria

• women who are not at high risk for postpartum hemorrhage , or attending for normal vaginal delivery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study	Tranexamic acid injection	Tranexamic acid 1 gm (100 mg/ml) slowly intravenous infusion during delivery ( administered over 10 minutes at 1 ml/minute) .

Primary Outcome Measures

Name	Time	Method
blood loss	immediately after deliver	Estimation of blood loss

Secondary Outcome Measures

Name	Time	Method
blood pressure	immediately after delivery	blood pressure
pulse	immediately after delivery	pulse
temperature	immeditely after delivery	temperature

Trial Locations

Locations (1)

Police Hospital; 🇪🇬 Cairo, Egypt