Effects of Sage Extracts on Cognitive Function During Aerobic Exercise
- Conditions
- Healthy
- Interventions
- Dietary Supplement: PlaceboDietary Supplement: Sage extracts Cognivia
- Registration Number
- NCT04804657
- Lead Sponsor
- University of Burgundy
- Brief Summary
Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in fatiguing conditions. The current study investigates the effects of this supplementation in healthy males and females versus placebo on cognition, heart rate and perceived exertion, during a fatiguing cycling exercise.
- Detailed Description
Healthy males and females will be tested in fresh and fatiguing conditions to mimic individuals at the beginning or during a competition where cognitive function are important for decision making for example. Tests will be conducted during the warm-up (fresh), during fatiguing situations (during two consecutive 10-minutes pedaling exercises) and during recovery. Tests will include a reverse digit memory test (from 3 to 7 digits), a stroop test, a simple reaction time test. Moreover, heart rate and rating of perceived exertion will be quantified.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 17
- Body mass index lower than 27 and waist size lower than 94 cm
- physical activity higher than 3 hours a week
- written informed consent
- more than 12 hours training a week
- asthmatic, smokers or under medicinal drugs
- dietary supplement, sports drink, special dietary food or functional food, of any kind, liable or presented as liable to enhance physical performances
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description placebo Placebo Two hours before the endurance test, participants were asked to absorb two capsules of placebo (similar appearance than active comparator). Sage extract Sage extracts Cognivia Two hours before the endurance test, participants were asked to absorb two capsules of sage extracts (600mg each - cognivia™)
- Primary Outcome Measures
Name Time Method Memory During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period Changes in percent number of correct answers during a reverse digit immediate memory test
- Secondary Outcome Measures
Name Time Method Rating of perceived exertion At rest, at the end of the 10-minutes warm-up, at the end of the first 10-minutes fatiguing exercise, at the end of the second 10-minutes fatiguing exercise, after 5 minutes of recovery Changes in rating of perceived exertion using a visual analogic scale (1-10)
Reaction time During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period Changes in reaction time between a visual signal and manual action
Stroop reaction time During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period Changes in reaction time during the stroop test
Heart rate At rest, at the end of the 10-minutes warm-up, at the end of the first 10-minutes fatiguing exercise, at the end of the second 10-minutes fatiguing exercise, after 5 minutes of recovery Changes in heart rate using a polar belt (in beats per minutes)
Stroop performance During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period Changes in percent number of correct answers during a stroop test
Trial Locations
- Locations (1)
Centre d'Expertise de la Performance
🇫🇷Dijon, France