Cristalloid vs. colloid in patients with severe sepsis and septic shock.

Completed

• Conditions: Severe sepsis or septic shock.

• Registration Number: NL-OMON21828
• Lead Sponsor: one

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Sever sepsis or septic shock (according to the criteria of the American College of Chest Physicians / Society of Critical Care Medicine) in a mechanically ventilated ICU patient.

Exclusion Criteria

Patients under the age of 18 years and patients with a sensitivity to starch-products.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The relation between the resuscitation regime and the tissue oxygen tension. <br />Furthermore the relation between the resuscitation regime and the amount of extravascular lungwater, as well as the relation between the amount of extravascular lungwater and the tissue oxygen tension.

Secondary Outcome Measures

Name	Time	Method
1. Subcutaneous temperature; <br />2. Labaratory findings: hemoglobine, hematrocrite, albumine, arterial and venous bloodgasses; <br />3. Hemodynamic parameters: cardiac output, VO2, DO2; <br />4. Respiratory parameters: PEEP, PaO2/FiO2 ratio; inotropes.