跳至主要内容
临床试验/CTRI/2023/02/049983
CTRI/2023/02/049983已完成不适用

Effectiveness of Ancillary Cardio-respiratory Therapeutic Regimen on Post Operative Pulmonary Dysfunction and Quality of Life after CABG surgery – A Pilot Study

Chettinad academy of research and education (CARE)1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年2月27日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40
试验地点
1
主要终点
Pulmonary function test, Numerical pain rating scale(NPRS) Physical Functional capacity, Quality of Life Length of hospital stay Secondary outcome Heart rate variability during TENS

研究概览

简要总结

Coronary artery bypass graft(CABG) is a major surgical procedure. Approximately 7 million open heart surgeries are performed worldwide annually, and 30% of patients experience major post-operative complications. currently, in India, CABG accounts for more than 60% of all cardiac surgeries performed in India. Generally, after CABG, elevated lactate, and decreased central venous oxygenation promote tissue perfusion, and post-operative pain adversely affects coughing and deep breathing resulting in pulmonary complications, including retention of pulmonary secretion and atelectasis. pneumonia, pleural effusion, respiratory failure, and even death. Combined Non-invasive ventilation therapy, and respiratory and physical exercises have significantly improved the acute phase I of cardio-pulmonary rehabilitation programs and physical functional capacity after CABG. However, critical research gaps persist in preventing the in-patients ’ tissue perfusion and operative pulmonary complications associated with pain, physical functional capacity, and quality of life.

Hypothesis - To emphasize a well-defined ancillary cardio-respiratory therapeutic regimen to increase central venous oxygenation and to reduce post-operative CABG pain in resting and coughing conditions to improve pulmonary functions, physical functional capacity, and quality of life after CABG.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Outcome Assessor Blinded

入排标准

年龄范围
40.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Good Left Ventricular function, Smokers, Diabetes, Hypertension, Dyslipidaemia, and Obesity.

排除标准

  • Chronic liver and renal impairment, unstable angina, Heart failure, pulmonary diseases (COPD and Asthma), COVID-19, Severe cardiac arrhythmia and post-operative uncontrolled diabetes and hypertension, History of stroke and motor disabilities.

结局指标

主要结局

Pulmonary function test, Numerical pain rating scale(NPRS) Physical Functional capacity, Quality of Life Length of hospital stay Secondary outcome Heart rate variability during TENS

时间窗: Baseline, Day 2, Day 7, Day 30

次要结局

  • Secondary outcome Heart rate variability during TENS(Baseline, Day 2,)

研究者

发起方
Chettinad academy of research and education (CARE)
申办方类型
Research institution and hospital

研究点 (1)

Loading locations...

相似试验