The Feasibility of Frame Running as an Exercise Option for People With Multiple Sclerosis With Impaired Balance and Mobility
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Queen Margaret University
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Frame Running shuttle run/walk test
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
There is ample evidence that regular exercise can reduce MS specific symptoms and improve health and wellbeing in people with MS. However, for people with MS to engage in exercise activities long term, it is important that they are offered a range of exercise opportunities that are safe, feasible and potentially effective to reduce MS symptom. This will allow people to select an activity they enjoy, is adapted to their needs and thus are more sustainable long-term. Frame Running (FR) provides an opportunity for people with walking and balance problems to walk or run safely without the risk of falling. The frame consists of three wheels and has a saddle and handlebars like a trike without pedals. The proposed mixed methods study aims to examine the feasibility and acceptability of FR as a sustainable aerobic exercise option for people with MS and the feasibility of conducting a future definite trial into the impact of FR on functional mobility, fatigue, cardiorespiratory function and psychosocial outcomes. People who experience problems with their walking and/or balance will be eligible to take part in this study which consists of a 12 weekly group FR training sessions led by a qualified coach. FR training attendance, recruitment, retention, outcome measure completion and adverse events will be recorded and the participant views on the feasibility, acceptability and impact of FR will be explored through the use of focus groups. Physical function, physical activity and psychosocial outcomes will be assessed at baseline, 6 and 12 weeks.
Investigators
Marietta van der Linden
Senior research fellow
Queen Margaret University
Eligibility Criteria
Inclusion Criteria
- •People with a definite diagnosis of MS according to the revised MacDonald criteria, aged 18 and over, experiencing walking or balance difficulties but able to transfer independently will be eligible to take part in this study. This equates to people with an EDSS of 3.5 to
- •In order to be eligible for taking part in the Frame Running sessions, people should also be able comprehend and follow instructions relating to participation training as well as have sufficient understanding of the English language to complete the consent forms and questionnaires
Exclusion Criteria
- •Those with contraindications to exercise, those unable to safely propel the frame for any distance on their own using the try-out sessions and those with more than 10 hours of FR experience will be excluded from participation in this study. Other exclusion criteria are lower limb surgery less than 3 months prior to the start of the study, having started disease modifying and/or spasticity treatment less than 3 months prior to the start of the study and severe visual impairment affecting the ability to safely take part in Frame Running training sessions.
Outcomes
Primary Outcomes
Frame Running shuttle run/walk test
Time Frame: 12 weeks
test conducting on the running track, outcome is number of shuttles performed
Fatigue Scale for Motor and Cognitive Functions (FSMC)
Time Frame: 12 weeks
questionnaire (range 20 to 100) higher scores indicate higher self-reported fatigue
Resting blood pressure
Time Frame: 12 weeks
resting blood pressure in mmHg
weekly step count
Time Frame: 11 weeks
Measured using an ActivPAL activity monitor
Five times sit-to-stand test
Time Frame: 12 weeks
measurer of functional strength, Duration, measured in seconds
Psychological Impact of Assistive Devices Scale
Time Frame: 12 weeks
questionnaire (range -3 to 3) higher score indicate improvement in psychosocial impact
Canadian Occupational Performance Measure
Time Frame: 12 weeks
semi-structured interview (ratings range from 1 to 10, higher scores indicate higher perceived improvement in function
Godin Leisure time exercise questionnaire
Time Frame: 12 weeks
questionnaire (range 0-119) higher scores indicate higher level of leisure time exercise participation
Exercise Self Efficacy Scale
Time Frame: 12 weeks
questionnaire (range 10-40) higher scores indicate higher self-efficacy
six minute Frame Running test
Time Frame: 11 weeks
measured in meters travelled during 6 minutes, test conducted on a running track
Multiple Sclerosis Walking Scale
Time Frame: 12 weeks
questionnaire (range 12-60) higher scores indicate higher self-reported limitation in walking ability
Secondary Outcomes
- number of weekly training session attended(12 weeks)
- Heart rate during the training session(8 weeks)