Lymphadenectomy for Pancreatic Head Cancer: Standard or Extended?
Not Applicable
Completed
- Conditions
- Pancreatic Ductal Adenocarcinoma
- Interventions
- Procedure: Pancreaticoduodenectomy with Extended lymphadenectomyProcedure: Pancreaticoduodenectomy with Standard lymphadenectomy
- Registration Number
- NCT02787187
- Lead Sponsor
- Ruijin Hospital
- Brief Summary
The purpose of this study is to compare outcomes of patients undergoing standard or extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 230
Inclusion Criteria
- Pathologic diagnosis of pancreatic ductal adenocarcinoma
- Signed the informed consents
Exclusion Criteria
- Pathologic diagnosis of other pancreatic cancers
- Pre-operative anti-cancer treatment
- Recurrence patients
- Patients with contraindication(hepatic/ respiratory/ renal dysfunction, etc )
- Pre operative exam: Total bilirubin more than 250µmol/L
- AJCC stage IV
- Operation non radical
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Extended resection Pancreaticoduodenectomy with Extended lymphadenectomy Pancreaticoduodenectomy (child's digestive reconstruction)extended lymphadenectomy No8p 12a 12p 14c 14d 16 Standard resection Pancreaticoduodenectomy with Standard lymphadenectomy Pancreaticoduodenectomy (child's digestive reconstruction); Standard lymphadenectomy: No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b
- Primary Outcome Measures
Name Time Method All-cause mortality 3yrs post-operation
- Secondary Outcome Measures
Name Time Method all-cause mortality 1yr post-operation
Trial Locations
- Locations (1)
Shanghai Ruijin Hospital
🇨🇳Shanghai, Shanghai, China