Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 135,877
- 试验地点
- 1
- 主要终点
- MACCE
研究概览
简要总结
For the management of low-density lipoprotein-cholesterol (LDL-C), some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in LDL-C levels. High-intensity or maximally tolerated intensity can be maintained without a target goal. However, the European guideline recommends less than 55 mg/dL of LDL-C after PCI.
详细描述
To investigate the Optimal Attained LDL-C Levels in Patients Who Achieved ≥50% LDL-C Reduction After PCI.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients receiving PCI with health check up before and after PCI within 3 years
排除标准
- •Patients receiving statin before PCI
- •Patients with liver cirrhosis
- •Patients with cancer
- •Patients without prescription of statin
- •Patients with LDL-C <55 mg/dL before PCI
研究组 & 干预措施
>=50% LDL-C reduction
LDL-C reduction >=50%
Further divided by LDL <55mg/dL 55< LDL < 70 mg/dL LDL > 70 mg/dL
干预措施: LDL reduction therapy (Drug)
<50% LDL-C reduction
LDL-C reduction <50%
干预措施: LDL reduction therapy (Drug)
结局指标
主要结局
MACCE
时间窗: 10 years after PCI
major adverse cardiac and cerebrovascular events
次要结局
- Cardiovascular death(10 years after PCI)
- Repeat revascularization(10 years after PCI)
- Spontaneous myocardial infarction(10 years after PCI)
- Ischemic stroke(10 years after PCI)
研究者
Ki Hong Choi
Professor
Samsung Medical Center