The neuronal correlates of reward and executive function interactions in adolescents with ADHD
Completed
- Conditions
- Attention deficit/hyperactivity disorder (ADHD)10009841
- Registration Number
- NL-OMON37254
- Lead Sponsor
- Radboud Universiteit Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
20 typically developing children and adolescents
20 children and adolescents with AD/HD-Combined Type (AD/HD-C).
20 children and adolescents with AD/HD-Inattentive Type (AD/HD-I).
All participants will be between 12-17 years old, and the groups will be matched for age
Exclusion Criteria
- Use of psychoactive medication that cannot be discontinued (participants who do take psychostimulant drugs will discontinue at least 24 hours before the experiment)
- Intelligence level < 75
- Learning disabilities
- Neurological conditions
- Comorbid conditions except for Oppositional Defiant Disorder and Conduct Disorder
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Behavioural performance on both cognitive tasks (response inhibition and<br /><br>cognitive flexibility) during monetary motivation compared to no external<br /><br>motivation.<br /><br>- Brain activation during response inhibition and cognitive flexibility during<br /><br>monetary motivation compared to no external motivation.<br /><br>- DAT genotype</p><br>
- Secondary Outcome Measures
Name Time Method <p>IQ (abbreviated IQ test)<br /><br>Symptom severity (measured with questionnaires and screening interview)</p><br>