Randomized double-blind study for the effect of highly absorptive curcumin on left ventricular diastolic function in hypertensive patients with hypertrophied hearts - Randomized double-blind study of highly absorptive curcumin in hypertensive patients with hypertrophied hearts

ational Hospital Organization Kyoto Medical Center0 个研究点目标入组 230 人开始时间: 2014年6月11日最近更新: 2023年10月17日

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•1) Chronic atrial fibrillation 2) Unstable angina, recent (< 3 months), myocardial infarction, severe coronary heart disease (left main trunk or 3 vessel disease), and recent (=< 3 months) o planned (=< 6 months) AC bypass furgery/PCI 3) Severe arrhythmia (sustained ventricular tachycardia, ventricular fibrillation, and severe bradycardia with an indication of pacemaker implantation 4) Moderate or severe valvular diseases 5) Cardiomyopathy or progressive myocarditis 6) Severe respiratory diseases 7) Cardiogenic shock or systolic blood pressure < 80 mmHg 8) Severe liver dysfunction or liver cirrhosis 9) Renal failure (Cre >=4.0 mg/dL or dialysis) 10) Recent (< 3 months) cerebrovascular disease 11) Malignancy 12) Poorly controlled diabetes (HbA1c >=8.0%) 13) Anemia (Hb < 6.0 mg.dL) 14) Use of steroid 15) Past history of curcumin allergy 16) Pregnancy, nursin g or a wish for pregnancy within next 6 months 17) etc

发起方

ational Hospital Organization Kyoto Medical Center