NCT02291718已完成4 期
Comparison of High Iodine Concentration Contrast Material (Isovue 370) vs Standard Protocol (Isovue 300) in Thoracoabdominal Aortic Computed Tomographic Angiography (CTA) for Radiation Dose Reduction
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Radiation Dose
研究概览
简要总结
The purpose of this study is to compare the contrast agents and imaging techniques used for thoracoabdominal aortic imaging in CT. Imaging parameters and contrast volume are changed and adjusted based on the contrast agent, since contrast agents have varying iodine concentrations. If the contrast iodine concentration is higher, it may be possible to adjust the imaging parameters and lower the overall radiation dose to the patient.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing thoracoabdominal aortic (TAA) CTA
- •Able to provide informed consent
- •Body Mass Index (BMI) equal to or less than 30
排除标准
- •Creatinine greater than 2.0
- •Allergy to contrast media
- •Pregnant women
研究组 & 干预措施
Isovue 370 60mL
Active Comparator
Isovue 370 60mL injected 100 kVp 240 mAs
干预措施: Isovue (Drug)
Isovue 300 75mL
Active Comparator
Isovue 300 75mL injected 120 kVp 250 mAs
干预措施: Isovue (Drug)
Isovue 370 75mL
Active Comparator
Isovue 370 75mL injected 100 kVp 240 mAs
干预措施: Isovue (Drug)
结局指标
主要结局
Radiation Dose
时间窗: 30 minutes
次要结局
- Signal to Noise Ratio(30 minutes)
- Hounsfield Unit Attenuation Values(30 minutes)
- Variation in Contrast for the Entire Vascular System (coV)(30 minutes)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)Coronary Artery DiseaseNCT02184117The University of Texas Health Science Center, Houston763
招募中
4 期
Chest CT Using Low-concentration Iodine Contrast MediaPulmonary DiseaseNCT05967117Jung Im Jung370
已完成
不适用
Comparison of Contrast Agent Administration ProtocolsRadiography, ThoracicNCT04300972Oslo University Hospital67
已完成
4 期
Effects Contrast on Platelet Activity, Thrombosis and Fibrinolysis in Patients Undergoing Coronary AngiographyCoronary Artery DiseaseNCT01848899NYU Langone Health100
已完成
3 期
Comparison of Isovue 370 vs. Standard Protocol in Coronary Computed Tomographic Angiography (CTA)Coronary Computed Tomographic AngiographyNCT02171247Duke University35