A randomised controlled clinical trial to evaluate the efficacy of Gugguladi Karnadhoopan against Clotrimazole 1% ear drops in Otomycocis.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- the efficacy of gugguladi Karnadhoopan in comparison with clotrimazole 1% ear drops to reduce symptoms of otomycosis viz otalgia,itching,heaviness in ear,discharge from ear will be evaluated.
研究概览
简要总结
Otomycosis is one of the commonest infection seen in the external auditory canal . It is the superficial,diffused fungal infection of the ear canal with symptoms of Otalgia ,itching ,heaviness in ear and discharge from ear . Conventionally clotrimazole ear drops is the prescribed line of treatment . In ayurveda symptoms of otomycosis corelate with kaphaj karnashoola. The ratio of otomycosis is increasing day by day with increased instillation of different otic drops and use of antibiotics and corticosteroids . With random use of antibiotics many patients are becoming resistant to it. Dhoopan is the effective therapy for otomycosis. Gugguladi karnadhoopan is taken for study to check its effectiveness in comparison with conventional clotrimazole 1% ear drops in the treatment of otomycosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having minimum 3 symptoms of otomycosis-otalgia,itching,heaviness in ear,discharge from ear.
排除标准
- •Patients having otomycosis with discharge due to secondary bacterial infections.
- •Patients having complications of aural polyp,maggots,perforated Tympanic membrane,cholesteatoma.
结局指标
主要结局
the efficacy of gugguladi Karnadhoopan in comparison with clotrimazole 1% ear drops to reduce symptoms of otomycosis viz otalgia,itching,heaviness in ear,discharge from ear will be evaluated.
时间窗: 7 days treatment with follow-up on 8th day.
次要结局
- to assess the efficacy of gugguladi karnadhoopan in the management of otomycosis.(to assess the efficacy of clotrimazole 1% ear drop in the management of otomycosis.)
研究者
Dr Pratik Laxman Kumbhar
PDEAs College of Ayurved and Research Centre