The prepare multi-morbid older people for end-stage kidney disease trial

orth Bristol NHS Trust0 个研究点目标入组 448 人开始时间: 2017年5月31日最近更新: 2024年9月9日

适应症

试验速览

2021 Other publications in https://pubmed.ncbi.nlm.nih.gov/32940683/ Background and recruitment progress (added 05/05/2023)

•Patients known to renal services with new or existing stage 5 CKD (eGFR <15, with at least one result confirming this in the last 12 months) and:
•1. Aged 65+ with a World Health Organisation (WHO) performance status 3+ (0 = Fully active, able to carry out all normal activity without restriction; 1 = Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature; 2 = Ambulatory and capable of all self-care but unable to carry out any work activities; up and about more than 50% of waking hours; 3 = Symptomatic and in a chair or in bed for greater than 50% of the day but not bedridden; 4 = Completely disabled; cannot carry out any self-care; totally confined to bed or chair), or
•2. Aged 65+ with a Davies co-morbidity score 2+ (each of the following scores one point: Malignancy, ischaemic heart disease, peripheral vascular disease (including stroke), left ventricular dysfunction, diabetes mellitus, systemic collagen vascular disease, other significant pathology (including COPD, cirrhosis, psychiatric illness, HIV), or
•3. Aged 80+

•1. Unable to consent, e.g. significant cognitive impairment or psychiatric disorder
•2. Not medically fit for dialysis
•3. Within 4 weeks of starting dialysis
•Added 01/07/2019:
•4. Patients that have had a previous kidney transplant
•5. Patients that are 'active' on the kidney transplant waiting list or being worked up for the kidney transplant waiting list

发起方

orth Bristol NHS Trust