Longitudinal Geriatric Assessment to Optimize Outcomes of Older Patients With Muscle-Invasive Bladder Cancer After Radical Cystectomy: A Pilot Trial

University of Kansas Medical Center0 sitesSeptember 14, 2022

ConditionsUrinary Bladder Cancer

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Urinary Bladder Cancer
Sponsor: University of Kansas Medical Center
Primary Endpoint: Develop a geriatric oncology assessment clinic and workflows
Status: Withdrawn
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

This single arm pilot study will evaluate the feasibility and acceptability for perioperative Comprehensive Geriatric Assessment (CGA) and CGA-directed supportive and restorative care for patients with muscle-invasive bladder cancer who are planned to undergo preoperative chemotherapy.

Registry

clinicaltrials.gov

Start Date

September 14, 2022

End Date

August 21, 2023

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Kansas Medical Center

Responsible Party

Principal Investigator

Elizabeth Wulff-Burchfield, MD

Assistant Professor

University of Kansas Medical Center

Eligibility Criteria

Inclusion Criteria

•Ability of participant OR Legally Authorized Representative (LAR) to understand this study, and participant or LAR willingness to sign a written informed consent
•Males and females age ≥ 65 years
•Diagnosis/disease status
•Histologically proven muscle-invasive bladder cancer (MIBC) without metastatic disease.
•Patients planning to undergo neoadjuvant chemotherapy and radical cystectomy for MIBC.
•Treatment with investigational systemic therapy is permitted if participants will be receiving chemotherapy as part of their treatment plan

Exclusion Criteria

•Diagnosed with a psychiatric illness or is in a social situation that would limit compliance with study requirements
•Any other known invasive malignancy within previous 2 years with the following EXCEPT: low grade prostate cancer on active surveillance, chronic lymphocytic leukemia CLL on surveillance / observation, non-melanoma skin cancers

Outcomes

Primary Outcomes

Develop a geriatric oncology assessment clinic and workflows

Time Frame: 12 months

Develop a geriatric oncology assessment clinic and workflows for the University of Kansas Health System, including University of Kansas Cancer Center St. Francis and Great Bend practices.