The Effect of Short-term Aronia Melanocarpa Extract Supplementation on Cognitive Function in Healthy Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Cognitive function
研究概览
简要总结
There is a great interest in improving cognitive performance, including memory and attention. Improved attention is desirable for a large group of people because it is linked to improved performance . Students and professionals can benefit from improved attention and thus performance in academic and other work environments. In addition, cognitive functioning also plays an important role in sports. Various cognitive skills, including attention, reaction time and motor function, have shown that they can influence sport performance. A completely natural supplement with aronia melanocarpa extract could be a promising way to naturally improve cognitive performance.
详细描述
There is a great interest in improving cognitive performance, including memory and attention. Improved attention is desirable for a large group of people because it is linked to improved performance. Students and professionals can benefit from improved attention and thus performance in academic and other work environments. In addition, cognitive functioning also plays an important role in sports. Various cognitive skills, including attention, reaction time and motor function, have shown that they can influence sport performance. A completely natural supplement with aronia melanocarpa extract could be a promising way to naturally improve cognitive performance. The product in this study is aronia melanocarpa which contains polyphenols. A limited number of clinical studies have already been carried out to see the effect of similar products on cognitive functioning. However, these studies have often been done in older study populations or over a longer period of time. In this study, in healthy adolescents (ages between the 18-35 and with a BMI between 18.5 and 30), the investigators want to test the short term (7 days) effect of aronia melanocarpa extract on cognitive functioning. The investigators will also test the effect of supplementation on the particpant's mood, vascular function, blood biomarkers, retinal vasculature, and subjective cognition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
盲法说明
block randomization
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy young adults: ages between 18 and 35
- •BM between 18.5-30 kg/m2
排除标准
- •Current use of (antioxidant) dietary supplements and not willing to quit for the duration of the study duration
- •Pre-existing or history of neurological illness
- •High blood pressure (>140 systolic and/or >90 diastolic mmHg)
- •Use of medication that might have influence on endpoints (e.g. antidepressant)
- •Known pregnancy or lactation
- •Food allergy to the study product
- •Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study, to be decided by the principle investigator, in the 180 days prior to the study
- •Abuse of products (> 20 alcoholic consumptions per week and drug usage)
- •Participation in a scientific intervention study which may interfere with this study in the 180 days prior to this study
研究组 & 干预措施
placebo
microcrystalline cellulose supplementation
干预措施: Placebo (Dietary Supplement)
Aronia
aronia melanocarpa supplementation
干预措施: Aronia (Dietary Supplement)
结局指标
主要结局
Cognitive function
时间窗: After 7 days of supplementation
CANTAB
次要结局
- Mood(After 7 days of supplementation)
- Vascular function(After 7 days of supplementation)
- Biomarkers in blood and saliva(After 7 days of supplementation)
- Subjective cognition(After 7 days of supplementation)
- Microvasculature(After 7 days of supplementation)