The quality of recovery of opioid free anaesthesia with superficial cervical plexus block vs opioid based anaesthesia in thyroid and parathyroid surgeries-A prospective randomised controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- quality of recovery 15 score at 24 hours after surgery based on QOR 15 questionnaire between the 2 groups
研究概览
简要总结
The aim of this study is to evaluate the quality of recovery between opioid free anaesthesia combined with superficial cervical plexus block and opioid based anaesthesia in thyroid and parathyroid surgeries.
Primary Objective- quality of recovery 15 score at 24 hours after surgery based on QOR 15 questionnaire between the 2 groups
Secondary Objective- QoR 15 at 48 hours , 72 hours PONV incidence and severity, length of hospital stay, pain score . After obtaining informed written consent from patients, all patients of age 18-70 years posted for thyroid and parathyroid surgeries will be randomly allotted into two groups: Group F and Group B. Randomisation will be done using computer-generated sequence of random numbers in 1:1 ratio. Group F- (n=38) patients receiving ketamine, loading dose of dexmedetomidine followed by its maintenance infusion and B/L superficial cervical plexus block
Group B- (n=38) patients receiving Injection remifentanil bolus for induction and its maintenance infusion. Both groups compared for quality of recovery post operatively in terms of quality of recovery 15 questionnaire.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of ASA grade1, II Patients scheduled for thyroid and parathyroid surgeries.
排除标准
- •Age less than 18 years Patients with a history of infection at the surgical site Patients with coagulation dysfunction.
- •Patients who were chronically treated with beta-blockers with pulse rate less than 50/min Patients with known history of drug allergy Renal or hepatic impairment Patient taking opioid for chronic pain.
结局指标
主要结局
quality of recovery 15 score at 24 hours after surgery based on QOR 15 questionnaire between the 2 groups
时间窗: quality of recovery 15 score at 24 hours after surgery based on QOR 15 questionnaire between the 2 groups
次要结局
- QoR 15 at 48 hours , 72 hours PONV incidence and severity, length of hospital stay, pain score(24 hours)
研究者
Devanshu Ranjan
IGIMS, Patna