DRKS00011023进行中（未招募）4 期
Therapeutic drug Monitoring (TDM) of piperacillin in patients with fever in neutropenia in the course of myelosuppressive cytostatic chemotherapy - TARGET-F
niversitätsklinikum Jena0 个研究点目标入组 38 人开始时间: 2016年9月2日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 38
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Fever (defined as 1 episode >38,3°C or 2 episodes >38,0°C within 2 hours) in neutropenia (defined as WBC < 1 Gpt/l or neutrophile granulocytes <0,5Gpt/l) following myelosuppressive chemotherapy
- •imminent or ongoing therapy with Piperacillin/Tazobactam (Pip/Taz)
- •signed informed consent
排除标准
- •Age < 18 years
- •Pregnancy/Breastfeeding
- •Women at prolific age without dependable contraception
- •Patients unable to consent
- •Medical history-documented hypersensitivity toward beta-lactam antibiotics or components of the study drug formulation (Pip/Taz)
- •Treatment with Pip/Taz at daily dose >18g within the last 24 hours before randomization
- •Participation in another interventional clinical trial
- •Prior participation in the current trial (TARGET-FN)
- •Impaired liver function (Child-Pugh C)
- •Renal failure (eGFR <40ml/min)
- •Infectious condition that requires a defined different antibiotic therapy (e.g. endocarditis)
- •Life expectancy < 90 days
研究者
相似试验
进行中（未招募）
1 期
Assessment of the optimal dosing of piperacillin-tazobactam in intensive care unit patients: extended versus continuous infusioPatients admitted on the intensive care unit (surgical and medical surgery)EUCTR2010-021050-20-BEGhent University Hospital30
招募中
3 期
Assessment of Memantine Drug Levels in Blood Among Indian Patients with Brain Metastases Treated with Radiation TherapyCTRI/2024/04/066217Amrita School of Pharmacy
招募中
不适用
Comfirmation of therapeutic drug monitoring for pulmonary hypertensiopulmonary hypertensionJPRN-UMIN000022593Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine50
招募中
不适用
TDM in MMTOpiod dependenceMental Health - AddictionACTRN12606000033549The Langton Centre90
招募中
4 期
Therapeutic drug monitoring in tocilizumab-treated rheumatoid arthritis patients: Pilot study of a double-blind randomised controlled trialrheuma10003816rheumatoid arthritisNL-OMON44574Amsterdam Rheumatology and immunology Center | Reade30