A clinical trial to study the advantage of using concentrated autologous platelets along with a bioactive composite in the treatment of periodontal defects
Phase 1
- Registration Number
- CTRI/2008/091/000285
- Lead Sponsor
- Sree Chitra Tirunal Institute of Medical Science and Technology,Thiruvananthapuram- 692012, Kerala
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Patients with normal health and with no complicating medical history that would contra-indicate routine periodontal surgery.
2. Patient age between 35and 44 years.
3. Presence of two or more sites in different quadrants with probing pocket depth ranging between 5 - 10 mm. The sites should exhibit clinical and radiographic evidence of intrabony defects.
4. Defects at balanced sites so that one could be used as control.
5. No history of allergy to any systemic analgesics or antibiotics.
Exclusion Criteria
1. Patients with systemic diseases.
2. Pregnant and lactating women.
3. Smokers and those with the habit of using tobacco.
4. Patients on anti-platelet drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Soft tissue parameters <br>1.Probing pocket depth. <br>2. Gingival margin level <br>3. Clinical attachment levelTimepoint: Immediate Pre-operative, 1 month, 3 months, 6 months, 9 months and 12 months
- Secondary Outcome Measures
Name Time Method Digital IOPA radiograpghTimepoint: Immediate Pre-operative, 1 month, 3 months, 6 months, 9 months and 12 months