A Prospective, Longitudinal Cohort Study of the Incidence of Dementia After the Onset of Delirium in Patients With Mild Cognitive Impairment: MDD Cohort (Mild Cognitive Impairment Delirium Dementia)

Keimyung University Dongsan Medical Center2 sites in 1 country163 target enrollmentJuly 1, 2021

ConditionsDelirium Mild Cognitive Impairment Dementia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Delirium
Sponsor: Keimyung University Dongsan Medical Center
Enrollment: 163
Locations: 2
Primary Endpoint: Dementia conversion rate and transition period in participants with mild cognitive impairment
Status: Recruiting
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Identify the degree of delirium in subjects with mild cognitive impairment and find the risk factors of delirium. Mortality, hospital stay, and medical expenses are analyzed as clinical consequences related to delirium incidence.
Dementia conversion rate and conversion period of subjects with mild cognitive impairment with delirium and it identifies the effect of delirium on dementia conversion.
Develop an AI(Artificial intelligence) algorithm for predicting dementia transition in subjects with mild cognitive impairment based on the research results of the 1st, 2nd, and 3rd years.

Registry

clinicaltrials.gov

Start Date

July 1, 2021

End Date

December 31, 2025

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Keimyung University Dongsan Medical Center

Responsible Party

Principal Investigator

Kyoung ja Moon

Assistant Professor

Keimyung University Dongsan Medical Center

Eligibility Criteria

Inclusion Criteria

•Patients 65 years of age or older who are admitted to a LTC
•Patients diagnosed with mild cognitive impairment by doctors
•Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination

Exclusion Criteria

•Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems
•Patients with serious psychiatric or neurological diagnosis,Patients who expire or were transferred on the day of admission -
•Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances

Outcomes

Primary Outcomes

Dementia conversion rate and transition period in participants with mild cognitive impairment

Time Frame: The participant's dementia conversion is checked in units of 1 month, and the period until conversion to dementia is analyzed in units of 12 months for 36 months.

descriptive statistics

Delirium incidence in participants with mild cognitive impairment

Time Frame: The number of subjects evaluated as positive in the delirium assessment using S-CAM for 30 days from the 1st day of study participation is statistically calculated.

descriptive statistics

Secondary Outcomes

Risk factors affecting participants' delirium(On the first day of data collection, the characteristics of subjects are collected through medical records. After 12 months, the risk factors affecting the occurrence of delirium among the characteristics of the subject are analyzed.)
healthcare costs(From the healthcare costs consumed during the hospital length of stay, the direct healthcare costs used only for treatment are calculated in won units and analyzed in units of 12 months.)
Mortality(It is statistically calculated in 30-day, 60-day, 12-month, 24-month, and 36-month increments.)
hospital length of stay(The period from hospitalization to discharge is calculated in days and analyzed in units of 12 months.)