Management of Septic Non-union of the Tibia Using the "Induced Membrane" Technique

Completed

• Conditions: Septic Tibial Non-union
• Interventions: Other: Data collection

• Registration Number: NCT03940638
• Lead Sponsor: CHU de Reims

Brief Summary

The aim of the study was to assess clinical and radiological results with the "induces membrane" technique, described by A. C. Masquelet in 1986, in a series of patients with septic non-union of the tibia

Detailed Description

Septic tibial non-union is a therapeutic challenge that may even lead to amputation. Treatment often necessitates several chirurgical steps. It is agreed that resection must extend to several tissues (osteitis zone ans macroscopically pathological soft tissue), with associated non-union site stabilization ans effective antibiotic therapy.

In 1986, Pr A. C. Masquelet described a 2-step procedure called the induced membrane technique, to manage bone defects of varying severity. Initial results were encouraging but there have been few large homogeneous series specific to this technique in septic non-union.

Study Timeline

• Study Start: 2015-09
• Primary Completion: 2015-10
• Study Completion: 2015-11
• Status Verified: 2019-05
• Study First Submitted: 2019-05-06
• Study First Submitted QC: 2019-05-06
• Study First Posted: 2019-05-07
• Last Update Submitted: 2019-05-07
• Last Update Posted: 2019-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with septic non-union of the tibia	Data collection	-

Primary Outcome Measures

Name	Time	Method
Presence of Bone union	Day 0	Bone union was defined by 2 continuous cortices on 2 views (radiologic images comprising 2 perpendicular views of the affected segment)

Trial Locations

Locations (1)

Chu Reims; 🇫🇷 Reims, France