Comparing the sedative effect of intranasal fentanyl and intranasal ketamine in phacoemulsificatio

Phase 2

Conditions: Cataract surgery.
Unspecified cataract
H26.9

Registration Number: IRCT20170809035601N11

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 80

Inclusion Criteria

Patients who are candidates for Phacoemulsification cataract surgery
Patients who are satisfied to enter the study
Patients aged 30-75 years old
patients with ASA class 1 and 2

Exclusion Criteria

History of any allergy or allergic reaction to any of medications used in the study
History of head injurys
High intraocular pressure or intracranial pressure
Cardiovascular risk
Hypertension
Severe respiratory disease
Advanced liver disease
Epilepsy or history of seizure
Nervous system disorders
The presence of any tumor or brain metastasis
Use of any analgesic and anesthetic drug

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sedation level. Timepoint: After induction of anesthesia, during the procedure every 5 minutes. Method of measurement: Modified ramsay sedation scale (RSS).

Secondary Outcome Measures

Name	Time	Method
Mean Atrial Pressure. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pressure gauge.;Oxygen saturation percentage. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pulse oximetry.;Heart rate. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Pulse oximetry.;Adverse drug reaction. Timepoint: Before surgery, every 5 minutes during surgery and after the surgery every 10 minutes for 30 minutes in recovery. Method of measurement: Adverse drug reaction questionnaire.;Recovery time. Timepoint: From the end of the surgery to the time exit Recovery. Method of measurement: Minute.;Surgeon satisfaction. Timepoint: End of surgery. Method of measurement: Likert scale.