Fitness, Activity and Lung Cancer Study

Not Applicable

Completed

• Conditions: Lung Cancer
• Interventions: Other: Physical training; Other: As usual

• Registration Number: NCT01748981
• Lead Sponsor: Oslo University Hospital

Brief Summary

The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection. Furthermore, to study the effect of training on aerobic capacity, muscular strength, morbidity and survival. Physical activity level by accelerometers, body composition by DXA and quality of life will also be reported.

Detailed Description

Five year after surgery, all included patients will be reinvited to undergo a fourth health excame to study the long-term effects of exercise training on physical fitness, morbidity and survival.

Study Timeline

• Study Start: 2010-11
• Study First Submitted: 2011-08-08
• Study First Submitted QC: 2012-12-11
• Study First Posted: 2012-12-13
• Primary Completion: 2017-12
• Study Completion: 2018-06-20
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-09
• Last Update Posted: 2019-02-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

• Non smal cell lung cancer
• Patient living in Oslo or Akershus county and accepted for lung cancer surgery at Oslo University hospital and Akershus University hospital
• were able to read and speak Norwegian

Exclusion Criteria

• Mental incompetence or physical disability that makes it difficult to walk on a treadmill
• Treatment or medical complications affecting ability to participate in an exercise group
• > 79 years

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Physical training	Physical training	Exercise intervention.
As usual	As usual	Controls

Primary Outcome Measures

Name	Time	Method
Change in Maximal oxygen uptake (VO2max) from baseline	An expected average of two weeks before surgery (baseline), four to six weeks after surgery, after six months and after 5 years	Change in VO2max from before to after surgery to measure the effect of surgery, and after six months to measure the effect of high-intensity training intervention, and after five years to study long-term effects

Secondary Outcome Measures

Name	Time	Method
Change in Pulmonary function from baseline	Pulmonary function is measured three times; an expected average of two weeks before surgery, four to six weeks after surgery, after after six months and after five years.	Change in pulmonary function from before to after surgery and after the intervention

Trial Locations

Locations (1)

Oslo University Hospital; 🇳🇴 Oslo, Norway