Cardiorespiratory Fitness and Effect of Training After Lung Cancer Surgery. A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 71
- 试验地点
- 2
- 主要终点
- Change in Maximal oxygen uptake (VO2max) from baseline
研究概览
简要总结
The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection. Furthermore, to study the effect of training on aerobic capacity, muscular strength, morbidity and survival. Physical activity level by accelerometers, body composition by DXA and quality of life will also be reported.
详细描述
Five year after surgery, all included patients will be reinvited to undergo a fourth health excame to study the long-term effects of exercise training on physical fitness, morbidity and survival.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 30 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non smal cell lung cancer
- •Patient living in Oslo or Akershus county and accepted for lung cancer surgery at Oslo University hospital and Akershus University hospital
- •were able to read and speak Norwegian
排除标准
- •Mental incompetence or physical disability that makes it difficult to walk on a treadmill
- •Treatment or medical complications affecting ability to participate in an exercise group
- •> 79 years
研究组 & 干预措施
As usual
Controls
干预措施: As usual (Other)
Physical training
Exercise intervention.
干预措施: Physical training (Other)
结局指标
主要结局
Change in Maximal oxygen uptake (VO2max) from baseline
时间窗: An expected average of two weeks before surgery (baseline), four to six weeks after surgery, after six months and after 5 years
Change in VO2max from before to after surgery to measure the effect of surgery, and after six months to measure the effect of high-intensity training intervention, and after five years to study long-term effects
次要结局
- Change in Pulmonary function from baseline(Pulmonary function is measured three times; an expected average of two weeks before surgery, four to six weeks after surgery, after after six months and after five years.)
研究者
Elisabeth Edvardsen
Prinsipal Investigator
Oslo University Hospital