Cardiorespiratory Fitness and Effect of Training After Lung Cancer Surgery. A Randomized Controlled Trial
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Lung Cancer
- Sponsor
- Oslo University Hospital
- Enrollment
- 71
- Locations
- 1
- Primary Endpoint
- Change in Maximal oxygen uptake (VO2max) from baseline
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection. Furthermore, to study the effect of training on aerobic capacity, muscular strength, morbidity and survival. Physical activity level by accelerometers, body composition by DXA and quality of life will also be reported.
Detailed Description
Five year after surgery, all included patients will be reinvited to undergo a fourth health excame to study the long-term effects of exercise training on physical fitness, morbidity and survival.
Investigators
Elisabeth Edvardsen
Prinsipal Investigator
Oslo University Hospital
Eligibility Criteria
Inclusion Criteria
- •Non smal cell lung cancer
- •Patient living in Oslo or Akershus county and accepted for lung cancer surgery at Oslo University hospital and Akershus University hospital
- •were able to read and speak Norwegian
Exclusion Criteria
- •Mental incompetence or physical disability that makes it difficult to walk on a treadmill
- •Treatment or medical complications affecting ability to participate in an exercise group
- •\> 79 years
Outcomes
Primary Outcomes
Change in Maximal oxygen uptake (VO2max) from baseline
Time Frame: An expected average of two weeks before surgery (baseline), four to six weeks after surgery, after six months and after 5 years
Change in VO2max from before to after surgery to measure the effect of surgery, and after six months to measure the effect of high-intensity training intervention, and after five years to study long-term effects
Secondary Outcomes
- Change in Pulmonary function from baseline(Pulmonary function is measured three times; an expected average of two weeks before surgery, four to six weeks after surgery, after after six months and after five years.)