Erythrocytapheresis versus Phlebotomy as maintenance therapy in patients with hereditairy hemochromatosis; a randomised, single blinded, sequential, cross-over trial
- Conditions
- IronacumulationIronoverload10018849
- Registration Number
- NL-OMON33962
- Lead Sponsor
- Sanquin Bloedbank
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 48
Patients with ironoverload, homozygous for C282Y, treated with Phlebotomy as maintenance therapy for at least 6 month
Demonstrated therapy compliance with prescribed P so far
Ferritin level between 30-50 ug/L at start of the inclusion
Age 18 years an older
Weight > 50 kg
Signed informed consent
Willigness to fill out additional questionnaires at three points in time
Patients recieving others therapies such as chelating therapy or forced dietary regimen
Patients younger than 18 years
Patients with excessive overweight ( BMI>35)
Patients which are mentally incapacitade
Women being pregnant or expecting/planning to become pregnant during the two years period of the study
Patients with a malignancy
HH patients which are current blood donors
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method