The Effect of Dynamic Auditory Cueing on Spatial Neglect in Patients With Stroke: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Line Bisection Test (LBT) deviation score
研究概览
简要总结
Spatial neglect is a common condition after stroke and can make it difficult for people to pay attention to one side of space. This problem can negatively affect daily activities and functional independence. This study aims to evaluate whether dynamic auditory cueing for spatial neglect (DAC-SN) can improve spatial neglect in people with stroke. Participants are randomly assigned to one of two groups. One group receives conventional rehabilitation, while the other group receives conventional rehabilitation combined with dynamic auditory cueing. Dynamic auditory cueing uses moving sounds to guide attention toward the affected side. The intervention is applied for about ten minutes per day, five days a week, for four weeks. Spatial neglect and functional outcomes are assessed using standardized clinical tests and scales at baseline and at predefined time points during and after the intervention. The results of this study may provide evidence for the use of auditory-based approaches in the rehabilitation of spatial neglect after stroke.
详细描述
Spatial neglect is a common and disabling condition following stroke, characterized by reduced awareness of stimuli on one side of space. It is associated with impaired functional recovery and decreased independence in daily activities. Despite conventional rehabilitation approaches, spatial neglect may persist and continues to be a significant challenge in stroke rehabilitation. Dynamic auditory cueing for spatial neglect (DAC-SN) has been proposed as a method to facilitate attentional orientation by providing external sensory input directed toward the affected side. This approach may enhance spatial exploration and support recovery by promoting engagement with the neglected hemispace. The aim of this randomized controlled trial is to investigate the effect of dynamic auditory cueing in patients with stroke and spatial neglect. Participants are randomly assigned to receive either conventional rehabilitation alone or conventional rehabilitation combined with dynamic auditory cueing. The intervention is delivered in addition to standard rehabilitation in structured sessions over a four-week period. The control group receives conventional rehabilitation according to standard clinical practice. Spatial neglect severity and functional outcomes are assessed using standardized clinical measures at baseline and at predefined time points during and after the intervention period. The findings of this study are expected to provide evidence on the potential role of auditory-based interventions as an adjunct to conventional rehabilitation in improving spatial neglect and functional outcomes in patients with stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessors are blinded to group allocation. Due to the nature of the intervention, participants and therapists are not blinded.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years or older
- •Subacute or chronic stroke
- •Clinical diagnosis of left-sided spatial neglect confirmed by standardized tests (e.g., Line Bisection Test (LBT), Star Cancellation Test (SCT))
- •Normal or corrected visual acuity
- •Absence of auditory extinction
- •Ability to understand and comply with study procedures
- •Provision of written informed consent
排除标准
- •Hearing impairment (Hearing Handicap Inventory score ≥26)
- •Presence of hemianopia
- •Impaired visual acuity due to ocular pathology (e.g., cataract, glaucoma)
- •History of neurological disease (e.g., dementia, Parkinson's disease)
- •Structural brain lesions unrelated to stroke
- •Inability to participate in rehabilitation sessions or assessments
研究组 & 干预措施
Dynamic Auditory Cueing Group
Participants in this group receive dynamic auditory cueing for spatial neglect (DAC-SN) in addition to their standard conventional rehabilitation program. The intervention involves exposure to moving environmental sounds (such as animal or transportation noises) designed to redirect attention toward the neglected hemispace. The intervention is administered for 10 minutes per day, 5 days per week, over a total period of 4 weeks.
干预措施: Dynamic Auditory Cueing (Other)
Dynamic Auditory Cueing Group
Participants in this group receive dynamic auditory cueing for spatial neglect (DAC-SN) in addition to their standard conventional rehabilitation program. The intervention involves exposure to moving environmental sounds (such as animal or transportation noises) designed to redirect attention toward the neglected hemispace. The intervention is administered for 10 minutes per day, 5 days per week, over a total period of 4 weeks.
干预措施: Conventional Rehabilitation (Other)
Conventional Rehabilitation Group
Participants in this group receive only the standard conventional rehabilitation program provided by the clinic. This group does not receive dynamic auditory cueing for spatial neglect (DAC-SN). The frequency and duration of the standard therapy are matched to those of the experimental group to ensure a fair comparison of the additional effects of auditory cueing.
干预措施: Conventional Rehabilitation (Other)
结局指标
主要结局
Line Bisection Test (LBT) deviation score
时间窗: Baseline, after 1 session, after 10 sessions, and after 20 sessions (end of treatment)
The Line Bisection Test (LBT) is used to assess spatial bias by measuring deviation from the true midpoint of horizontal lines. Deviation toward the right side indicates more severe left-sided spatial neglect.
Catherine Bergego Scale (CBS) score
时间窗: Baseline and after 20 sessions (end of treatment)
The Catherine Bergego Scale (CBS) is used to assess the impact of spatial neglect on daily activities. Higher scores indicate greater severity of neglect in functional tasks.
次要结局
- Star Cancellation Test (SCT) score(Baseline, after 1 session, after 10 sessions, and after 20 sessions (end of treatment))
- Line Cancellation Test (LCT) score(Baseline, after 1 session, after 10 sessions, and after 20 sessions (end of treatment))
- Functional Independence Measure (FIM) score(Baseline and after 20 sessions)
- Center of Cancellation (CoC) value(Baseline, after 1 session, after 10 sessions, and after 20 sessions)
研究者
Elif Ezgi Kurtul, MD
Research Assistant, MD
Gazi University