Effectiveness and safety of TDCS in depressio
- Conditions
- Health Condition 1: F332- Major depressive disorder, recurrent severe without psychotic features
- Registration Number
- CTRI/2023/06/053834
- Lead Sponsor
- All India Institute of Medical Science New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.Age 18 to 55 years
2.Any gender
3.Right-handed subjects
4.Willing to give written informed consent
5.Ability to read Hindi or English language
6.Meeting DSM 5 criteria for Major Depressive Disorder (MDD)
7.Treatment naive or Treatment free from prior 2 weeks or on a stable standard antidepressant regimen with no change in treatment 4-weeks prior to tDCS intervention
8.HAMD score >= 17 (moderate to severe depression)
1.Suffering from any other psychiatric disorder or substance use disorder (except caffeine & nicotine) assessed through clinical interview using DSM 5
2.Persistent Depressive Disorder (dysthymia), Premenstrual Dysphoric Disorder, Depressive Disorder Due to Another Medical Condition, Substance/ Medication Induced Depressive Disorder, Other and Unspecified Depressive Disorders based on DSM 5
3.History of seizures
4.Pregnancy/ Lactation
5.Uncontrolled medical illness
6.History suggestive of space occupying brain lesion or cerebrovascular accident
7.Patient having implanted device or metal in brain/head or cardiac pacemaker
8.Allergic to radioligands
9.History of receiving any neuromodulation therapy (e.g., ECT, rTMS, tDCS) within the last 3-months
10.Actively suicidal as defined by a score of 4 on item 3 of HAMD
11.Currently receiving any form of Cognitive Behavioral Therapy or any other Psychotherapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method