Constitution of ex Vivo Ovarian Tumor Models for the Validation of the Interest of Innovative Therapies and the Search for Tumor or Circulating Biomarkers Predictive of Treatment Response

Recruiting

• Conditions: Ovarian Cancer

• Registration Number: NCT03831230
• Lead Sponsor: Centre Francois Baclesse

Brief Summary

Development of ex vivo models of ovarian cancer, fallopian tubes or peritoneum.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-01-28
• Study First Submitted QC: 2019-02-04
• Study First Posted: 2019-02-05
• Study Start: 2019-03-07
• Status Verified: 2021-07
• Last Update Submitted: 2021-07-20
• Last Update Posted: 2021-07-21
• Primary Completion: 2024-08
• Study Completion: 2029-08

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 160

Inclusion Criteria

• Patient over 18 years old.
• Patient with ovarian cancer, carcinoma of the fallopian tubes, or histologically proven peritoneum. All FIGO stages are accepted for the study.
• Patient to be managed by surgery (laparoscopy and / or laparotomy).

Exclusion Criteria

• Pregnant woman
• Persons deprived of liberty or guardianship (including curatorship)
• History of any other clinically active malignancy in the last 5 years prior to inclusion

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rates of exploitable ex vivo tumor, blood and urine samples for performing predictive tests	Collection of blood, urine, tumor and ascite samples at the time of ovarian surgery	Number and quality of tumor, blood and urine samples that can be used to perform predictive tests of the response to treatment

Trial Locations

Locations (1)

Centre François BACLESSE; 🇫🇷 Caen, France