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The comparative study to evaluate the effect of palonosetron monotherapy versus palonosetron with midazolam combination therapy for prevention of postoperative nausea and vomiting in breast cancer surgery

Not Applicable
Completed
Conditions
Not Applicable
Registration Number
KCT0001114
Lead Sponsor
Pusan National University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
104
Inclusion Criteria

female patients with American Society of Anesthesiologists physical status 1-2, who were aged 18-60 years, and were scheduled to undergo general anesthesia and postoperative intravenous patient controlled analgesia for breast cancer surgery

Exclusion Criteria

psychiatric disease
chronic pain
history of preoperative analgesics
contraindication of fentanyl or midazolam
when the PCA cannot be applied to patients

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
complete response( no nause and no vomiting remaining patient controlled analgesia)
Secondary Outcome Measures
NameTimeMethod
sedaton, sleep
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