Prospective Study of Hypercoagulation in Pregnant Women
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pre-Eclampsia
- Sponsor
- Hillerod Hospital, Denmark
- Enrollment
- 600
- Locations
- 2
- Last Updated
- 20 years ago
Overview
Brief Summary
Pre-eclampsia is one of the most common causes of maternal and fetal morbidity and mortality. The aim of this study is to identify pregnant women at risk for pre-eclampsia or other cardiovascular complications at a very early state of the disease, and thereby improve the current method of screening.
Detailed Description
600 pregnant women will be included in the project and followed in a standardized manner during their pregnancy. On a regular basis blood- and urine samples will be taken throughout their pregnancy and until 1 month after delivery and analyzed for a large variety of coagulation factors in order to identify factors that might predict an increased risk of developing pre-eclampsia and/or cardiovascular events. In addition a DNA-sample is taken if consented in order to evaluate genetic factors.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Pregnant women attending the midwife at Hilleroed Hospital, Frederiksborg County, Denmark.
Exclusion Criteria
- •Mental disease.
- •Problems understanding or reading Danish.
Outcomes
Primary Outcomes
Not specified