Effect of Low-calorie Diet on Serum Lipids, Adipokines, Insulin Resistance and Also Body Composition in Women With Metabolic Syndrome
Not Applicable
Completed
- Conditions
- Weight LossInsulin ResistanceAdipokines
- Interventions
- Other: Low-calorie diet
- Registration Number
- NCT02087709
- Lead Sponsor
- Universidade Federal do Rio de Janeiro
- Brief Summary
The purpose of this study is to evaluate the effect of a hypocaloric diet on biomarkers associated with insulin resistance, metabolic profile and body composition in women with Metabolic Syndrome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
- BMI of 30-34.9 kg/m2, diagnostic of metabolic syndrome based on National Cholesterol Education Panel ATPIII (2002)
Exclusion Criteria
- Diabetes mellitus, non-treated thyroid disease, treatment with lipid-lowering drugs and glucocorticoids or weight loss treatment within the previous 3 months.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Low-calorie diet Low-calorie diet The subjects were prescribed a daily energy intake 500 kcal lower than the estimated energy requirement.
- Primary Outcome Measures
Name Time Method Weight Change from baseline at 3rd month Change from baseline weight (Kg) at 3rd month.
- Secondary Outcome Measures
Name Time Method Insulin resistance markers Change from baseline at 3rd month Change from baseline fasting glucose and insulin, homeostasis model assessment-insulin resistance and quantitative insulin sensitivity check index at 3rd month, samples were stored at -20 degrees.
Trial Locations
- Locations (1)
Federal University of Rio de Janeiro
🇧🇷Rio de Janeiro, RJ, Brazil