ACTRN12609000459224招募中不适用
Early switch from intravenous to oral antibiotics in treatment of acute Paediatric Osteomyelitis
Diana Lennon0 个研究点目标入组 100 人开始时间: 2009年6月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 6 Months 至 15 Years（—）
- 性别
- All
入选标准
- •Children who presented with a diagnosis of actute osteomyelitis with or without septic arthritis.
- •Osteomyelitis is defined as an acute disease with symptoms, clinical or radiological signs compatible with the disease, and with or without positive microbiology from a local bony lesion or blood culture.
- •Septic arthritis is defined by an acute disease with positive inflammatory or microbiology result in a joint aspirate.
排除标准
- •1) Chronic osteomyelitis
- •2) Vertebral osteomyelitis
- •3) Atypical causative organism including gram negative bacteria and resistant organisms
- •4) Children with a history of compound fracture or penetrating injury
- •5) Immunodeficiency
- •6) Multifocal disease
- •7) Failure to achieve defervescence within 10-14 days from initiation of intravenous antibiotics
- •8) Children unable to take oral antibiotics
- •9) History of penicillin anaphylaxis
研究者
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