Cognitive Impairment and Neuropsychiatric Manifestations of Neurobrucellosis
- Conditions
- Brucellosis
- Interventions
- Diagnostic Test: MoCA
- Registration Number
- NCT04301752
- Lead Sponsor
- Mansoura University Hospital
- Brief Summary
Brucellosis is a common zoonotic infection in many parts of the world including the Mediterranean and Middle Eastern countries.
Neurobrucellosis may develop at any stage of disease and may have widely variable manifestations, including encephalitis, meningoencephalitis, radiculitis, myelitis, peripheral and cranial neuropathies, subarachnoid hemorrhage, and psychiatric manifestations.
- Detailed Description
Brucellosis is a common zoonotic infection in many parts of the world including the Mediterranean and Middle Eastern countries.
Neurobrucellosis may develop at any stage of disease and may have widely variable manifestations, including encephalitis, meningoencephalitis, radiculitis, myelitis, peripheral and cranial neuropathies, subarachnoid hemorrhage, and psychiatric manifestations.
The aimed is to shed light to the obscure areas of diagnosis in neurobrucellosis and have detailed general and neurologic features
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 82
- Patients >18 years of age with laboratory-confirmed brucellosis
- Previous neuropsychiatric disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Non-neurobrucellosis MoCA Brucellosis not associated with neuropsychiatric manifestations Neurobrucellosis MoCA Brucellosis associated with neuropsychiatric manifestations
- Primary Outcome Measures
Name Time Method MoCA s 24 hours Cognitive function was assessed by using MoCA score. Cognitive impairment was considered present when MoCA scores were \<26 .
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mansoura University Hospital
🇪🇬Mansoura, Egypt