Everolimo in combination with Tacrolimus low doses versus Mycophenolate Sodium gastro-resistant coated tablets with low doses of Tacrolimus in Liver Transplant recipients de novo”

Hospital Geral de Fortaleza0 个研究点开始时间: 2018年4月1日最近更新: 2023年5月29日

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•Orthotopic whole organ liver transplant recipients; deceased donor; age above 18 years; both sexes; with graft functionality within 72h of reperfusion.

•Patients with pre-transplant protein and urinary creatinine ratio greater than 1mg / g or proteinuria 24h greater than 1g; multiple organ transplant recipients; patients with hypercholesterolemia (greater than 350 mg / dL) or hypertriglyceridemia (greater than 500 mg / dL) severe if use of lipid-lowering therapy with controlled hyperlipidemia will be accepted; previously transplanted liver patients who progressed with graft loss and in need of retransplantation; patients with positive serology for HIV; women who are pregnant, who are planning to become pregnant, are pregnant or breastfeeding, or do not agree to use effective methods of contraception; patients with difficult decision making who are not judged medically or mentally capable of providing informed consent on their own.

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