Comparative evaluation of the effect of common analgesics on pulpal sensibility tests in children aged between 6 to 8 years: A prospective, parallel design, randomized, controlled clinical trial’
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Intake of either acetaminophen or Ibuprofen may affect the pulpal response to the cold EPT test, especially in teeth with SIP.
研究概览
简要总结
Arriving at an accurate diagnosis is one of the most important steps before initiating any dental procedures. correct diagnosis is both an art and science, not only in adult dentistry but also in pediatric dentistry. Thus, clinicians must take into account various variables, including the results of clinical tests, radiographic findings, dental history, and their own clinical knowledge and experience to reach an accurate diagnosis.
Pulpal sensibility Tests such as the cold, heat, and electric pulp tests (EPT) are important tools in endodontic diagnosis. The cold test is one of the most common endodontic diagnostic tests for the indirect assessment of pulp vitality. It is usually performed in combination with EPT to increase the validity and reliability of the findings To date, research on the comparative effects of various analgesics on pulpal sensitivity tests in pediatric populations remains relatively limited. Therefore, this study aims to bridge this gap by conducting a comprehensive comparative evaluation. By systematically examining the effects of common analgesics on different pulpal sensibility tests, we can provide valuable insights into the potential interactions between pain management and diagnostic accuracy in pediatric dentistry.
Thus, the present study aimed to investigate the effect of 2 commonly used analgesics namely, ibuprofen and acetaminophen on pulpal sensibility test (cold test and EPT) results and evaluate the masking effect of these medications on endodontic symptoms in primary teeth
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 6.00 Year(s) 至 8.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Medically fit children aged between 6 and 8 years 2 Children who are mentally capable of communication and those who can follow the instructions and are able to interpret the pain perception appropriately 3 Primary teeth with severe irreversible pulpitis 4 Children who haven’t used any analgesics or central nervous system depressants in the past 6 hours prior to their visit 5 Children who are cooperative enough to undergo procedures.
排除标准
- •1 Children who could not take acetaminophen or ibuprofen 2 Children with toothache due to periapical disease 3 History of systemic mental or physical disorders.
结局指标
主要结局
Intake of either acetaminophen or Ibuprofen may affect the pulpal response to the cold EPT test, especially in teeth with SIP.
时间窗: evaluation will be done at 0,20.60 minutes of interval
次要结局
- masking effect of these analgesics on pulpal sensibility tests and consideringing the possibility of incorrect diagnosis(evaluation will be done at a 0–20, 60-minute interval)
研究者
DIVYA RAJPUROHIT
Pacific Dental College And Hospital Debari .