Implementation and Evaluation of an Evidence Based Comprehensive Antimicrobial Stewardship Interventions in Haematological Malignancy Patients
Trial Snapshot
- Phase
- Phase 3 4
- Status
- Recruiting
- Sponsor
- Enrollment
- 153
- Locations
- 1
- Primary Endpoint
- To optimise antibiotic therapy through Antimicrobial Stewardship Intervention among Haematological Malignancy patients.
Study Overview
Brief Summary
Cancer patients in India, exhibit a high prevalence to first line antibiotics. Blood stream infections are commonly reported in patients with haematological malignancies. Data is limited regarding epidemiological and antimicrobial resistance pattern among haematological malignancies patients in India. To avoid unnecessary use of broad-spectrum antimicrobials for unspecified durations, it is strongly advised to implement a risk-based strategy. Prudent utilisation of antimicrobials, monitoring resistance patterns through surveillance and engaging an active multidisciplinary are essential for reducing antimicrobial resistance and clinical outcomes.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 90.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •All adults ≥18 years of age diagnosed with HM on antibiotic.
- •Prescribers involved with antibiotic prescription in the treatment of HM patients.
- •Prescribers involved with antibiotic prescription in the treatment of HM patients, multidisciplinary (AMS) team.
Exclusion Criteria
- •Pregnant and lactating women.
- •Prescribers not involved with HM patients.
Outcomes
Primary Outcomes
To optimise antibiotic therapy through Antimicrobial Stewardship Intervention among Haematological Malignancy patients.
Time Frame: After 6 months
Secondary Outcomes
- Prospective audit & feedback by clinical pharmacist will aid in assessing & reducing potentially inappropriate therapy which will improve outcomes.
Investigators
Avvaru Deepthi
Kasturba Medical College