Investigating basic information of skin toxicity associated with molecularly-targeted drugs cetuximab and panitumumab, and an evaluation of the usefulness of a topical moisturizer in patients treated for colorectal carcinoma and head and neck cancer.
Not Applicable
- Conditions
- colorectal carcinoma and head and neck cancer
- Registration Number
- JPRN-UMIN000019896
- Lead Sponsor
- agoya city university, Dermatology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
Patient treated with anti-EGFR antibody drugs before Patient with retinoid and/or retinoid analog within two weeks of observation period Patient with large skin problems such as burn, psoriasis, scleroderma Patient with drug eruption within two weeks of observation period Patient with hemorrhagic diseases such as hemophilia, thrombopenia, purpura Patient regarded as ineligible for clinical study by investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method sebum capacity, water content of the stratum corneum, duaring 6 weeks from cetuximab or Panitumumab contained chemotherapy started
- Secondary Outcome Measures
Name Time Method skin findings(skin dryness,desquamation), subjective complaints duaring 6 weeks from cetuximab or Panitumumab contained chemotherapy started