Postoperative Respiratory Complications in adult elective neurosurgical population

Recruiting

• Conditions: Medical and Surgical, (2) ICD-10 Condition: G968||Other specified disorders of central nervous system,

• Registration Number: CTRI/2022/03/041373
• Lead Sponsor: Department of NeuroanaesthesiaNIMHANS

Brief Summary

In this dissertation, adult neurosurgical patients undergoing elective surgeries will be observed to determine the incidence of postoperative pulmonary complications (PPC) in the first seven days of surgery. Clinical examination ,monitoring, chest X ray, ultrasound of thorax will be utilised to detect the occurrence of PPCs. the perioperative factors which lead to PPCs will be identified. Lung ultrasound will be performed to determine lung ultrasound aeration score (LUAS) preoperatively and compared with post operative LUAS to determine its effect on development of PPCs and also to study the effect of ventilator strategies on change in LUAS.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-04
• Last Update Posted: 2023-05-09

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

1.Patients aged 18-75 years 2.Patients undergoing elective neurosurgery, both cranial and spinal surgery requiring general anaesthesia and controlled mechanical ventilation of the lungs during surgery.

Exclusion Criteria

patients who are intubated prior to surgery,patient refusal, pregnant women, patients who are not extubated after surgery, patient who underwent General anaesthesia in previous 1 month.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome:	1week after surgery
1] To estimate the incidence of PPCs in elective neurosurgical procedures and to determine	1week after surgery
the perioperative factors contributing to PPCs.	1week after surgery

Secondary Outcome Measures

Name	Time	Method
1.To determine the effect of change in lung ultrasound aeration score on postoperative pulmonary complications 2.to determine the effect of intra operative ventilatory parameters on change in lung ultrasound aeration score and development of postoperative pulmonary complications	On the day of surgery, postoperative day 1, 1week after Surgery

Trial Locations

Locations (1)

National Institute of mental health and neurosciences; 🇮🇳 Bangalore, KARNATAKA, India

National Institute of mental health and neurosciences

🇮🇳Bangalore, KARNATAKA, India

SBDeepti Chandana

Principal investigator

7032369175

dr.deepti92@gmail.com