Psychophysiological Correlates of Mindfulness and Attention in Recurrent Depression and Healthy Volunteers
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- Relapse (MDE)
Study Overview
Brief Summary
The study investigates cognitive attention, rumination and psychophysiological (EEG) processes in healthy subjects and remitted patients with at least three previous depressive episodes. The investigators expect that Mindfulness Based Cognitive Therapy prevents future depressive episodes and has influence on cognitive and psychophysiological measures.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Factorial
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •recurrent depression with at least 3 previous MD-episodes, currently remitted (no symptoms)
Exclusion Criteria
- •current depression
- •lifetime schizophrenia
- •bipolar or schizoaffective disorder
- •any neurological disorders
- •other psychopathology during last 3 years
Arms & Interventions
Wait List Control
Patients do ot receive psychotherapy. The wait list control group will be assessed according to study protocol and offered MBCT after 6 month
Intervention: Waiting List Control (Other)
Mindfulness Based Cognitive Therapy
The published protocol of MBCT will be used. This is an eight week group program. Participants learn mindfulness techniques but also cognitive techniques to prevent new depressive episodes
Intervention: Mindfulness Based Cognitive Therapy (Behavioral)
Outcomes
Primary Outcomes
Relapse (MDE)
Time Frame: 12 month
Secondary Outcomes
- Electroencephalography (EEG)(6 month)
Investigators
Prof. Dr. Martin Hautzinger
University Professor of Clinical Psychology and Psychotherapy
University Hospital Tuebingen