A Comparison of the Post-operative analgesic effects of Propofol anaesthesia with Sevoflurane anaesthesia

• Conditions: Acute post-operative pain; MedDRA version: 9.1Level: LLTClassification code 10066714Term: Acute pain; MedDRA version: 9.1Level: LLTClassification code 10036286Term: Post-operative pain

• Registration Number: EUCTR2008-001052-48-IE
• Lead Sponsor: Coombe Women and Infants University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-03-03
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

American Society of Anesthesiologist classification I and II patients; aged over 18 years undergoing laparoscopic day case surgery.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Chronic pain states; known allergies or contraindications to the study medications; lack of informed consent; currently pregnant; currently breast feeding

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: To determine if intravenous propofol anaesthesia compared to inhalational sevoflurane has a postoperative analgesic effect in the immediate postoperative period.;Secondary Objective: To determine if intravenous propofol anaesthesia has a better quality of recovery compared to inhalational sevoflurane.;Primary end point(s): Pain score 0-10 measured on a visual analogue scale.<br>Cumulative morphine consumption.<br>Sedation score<br>Quality of recovery score (QoR-9 and QoR-40 scores)