Activation of Biobank for Association Study Between Environmental and Genetic Factors in Inflammatory, Functional and Neoplastic Bilio-pancreatic Diseases
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pancreatitis
- Sponsor
- IRCCS San Raffaele
- Enrollment
- 2000
- Locations
- 1
- Primary Endpoint
- The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
The purpose of establishing the biobank is to create a collection of biological material and clinical data, with a prospective and retrospective mold, in order to investigate the role of genetic predisposition in multifactorial bilio-pancreatic diseases, so that an evaluation of the possible association in the pathogenesis of exogenous factors with endogenous factors can be allowed.
Multifactorial diseases are in fact an expression of genetic predisposition upon which one or more environmental stimuli act. Usually the aforementioned factors are not capable individually of triggering disease but, when simultaneously present, can cause the pathological phenotype. Therefore, it becomes important in the description of disease pathogenesis to identify as many risk factors for disease prevention and early diagnosis.
Detailed Description
Samples collected depending on the disease: * Peripheral blood; * Portal blood; * Saliva; * Urine; * Stool; * Cystic fluid; * Pancreatic juice; * Biopsy tissue specimens;
Investigators
Paolo Giorgio Arcidiacono, MD
Professor
IRCCS San Raffaele
Eligibility Criteria
Inclusion Criteria
- •age \>= 18 years
- •signed informed consent
Exclusion Criteria
- •age \< 18 years
- •unwilling to sign informed consent
Outcomes
Primary Outcomes
The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers
Time Frame: Tthrough study completion, an average of 1 year
The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers will be evaluated by descriptive statistics and when available compared with that of subjects without such disorders (controls).