Outcome of Elderly Patients With Appendicitis

Completed

• Conditions: Appendicitis Acute
• Interventions: Procedure: Appendectomy

• Registration Number: NCT04791657
• Lead Sponsor: Gulhane Training and Research Hospital

Brief Summary

This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

Detailed Description

Appendicitis in elderly patients is more challenging due to delayed presentation and higher comorbidities, which is associated with increased postoperative morbidity and mortality. In this study, we aim to investigate the factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients. Records of patients who underwent appendectomy for appendicitis will be extracted. The primary outcome is 30-day postoperative complications. Independent variables examined include demographics, comorbidities, preoperative laboratory values, pathological findings, and surgical features. Both univariate and multivariate regression will be performed to identify factors associated with postoperative complications.

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2020-12-31
• Study Completion: 2020-12-31
• Status Verified: 2021-03
• Study First Submitted: 2021-03-07
• Study First Submitted QC: 2021-03-07
• Last Update Submitted: 2021-03-07
• Study First Posted: 2021-03-10
• Last Update Posted: 2021-03-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients aged 65 years and older
• Patients undergoing appendectomy for acute appendicitis (pathologically confirmed)
• Patients having complete records of clinical data and postoperative follow-up records

Exclusion Criteria

• Patients younger than 65 years
• Patients undergoing an appendectomy as part of another major operation or those with appendiceal malignancy
• Patients who are treated nonoperatively for acute appendicitis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients without complications	Appendectomy	Patients with uneventful recovery
Patients with complications	Appendectomy	Patients experiencing complications within 30 days postoperatively

Primary Outcome Measures

Name	Time	Method
30-day postoperative complication rate	30 days	The primary clinical outcome of interest is 30-day postoperative complications. The Clavien-Dindo classification will be used to grade postoperative outcomes and complications

Secondary Outcome Measures

Name	Time	Method
30-day readmission rate	30 days	30-day readmission is defined as unplanned readmission to the hospital within 30 days of discharge.
In-hospital mortality rate	30 days	In-hospital mortality is defined as death occurring during the hospital stay after the surgical procedure

Trial Locations

Locations (1)

Gulhane Training and Research Hospital; 🇹🇷 Ankara, Turkey