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Clinical Trials/NCT04791657
NCT04791657
Completed
Not Applicable

Factors Associated With Postoperative Complications After the Surgical Treatment of Appendicitis in Elderly Patients

Gulhane Training and Research Hospital1 site in 1 country80 target enrollmentJanuary 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Appendicitis Acute
Sponsor
Gulhane Training and Research Hospital
Enrollment
80
Locations
1
Primary Endpoint
30-day postoperative complication rate
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

Detailed Description

Appendicitis in elderly patients is more challenging due to delayed presentation and higher comorbidities, which is associated with increased postoperative morbidity and mortality. In this study, we aim to investigate the factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients. Records of patients who underwent appendectomy for appendicitis will be extracted. The primary outcome is 30-day postoperative complications. Independent variables examined include demographics, comorbidities, preoperative laboratory values, pathological findings, and surgical features. Both univariate and multivariate regression will be performed to identify factors associated with postoperative complications.

Registry
clinicaltrials.gov
Start Date
January 1, 2017
End Date
December 31, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Gulhane Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Suleyman Utku Celik

Principal Investigator

Gulhane Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients aged 65 years and older
  • Patients undergoing appendectomy for acute appendicitis (pathologically confirmed)
  • Patients having complete records of clinical data and postoperative follow-up records

Exclusion Criteria

  • Patients younger than 65 years
  • Patients undergoing an appendectomy as part of another major operation or those with appendiceal malignancy
  • Patients who are treated nonoperatively for acute appendicitis

Outcomes

Primary Outcomes

30-day postoperative complication rate

Time Frame: 30 days

The primary clinical outcome of interest is 30-day postoperative complications. The Clavien-Dindo classification will be used to grade postoperative outcomes and complications

Secondary Outcomes

  • 30-day readmission rate(30 days)
  • In-hospital mortality rate(30 days)

Study Sites (1)

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