Reducing Radioiodine Treatment in Low Risk Papillary Thyroid Cancer
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 61
- 主要终点
- Event free situation during follow-up event free /disease free
研究概览
简要总结
To study if its is safe to reduce the amount of postoperative treatments in those patients, who have been operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level.
详细描述
The purpose of the study : to enroll about 50 patients operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level.
Methods: either to follow-up patients according to the study protocol without radioiodine treatment or to give a radioiodine treatment with a dose of 1.1 GBq according to the normal Finnish treatment protocol for papillary thyroid cancer to those patients who themselves preferred to have a normal postoperative treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
盲法说明
No masking.
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •low risk papillary intrathyroidal thyroid cancer with diameter of 11-20mm
- •no lymphnode metastases
排除标准
- •high risk papillary cancer
- •mutlifocal papillary cancer
结局指标
主要结局
Event free situation during follow-up event free /disease free
时间窗: 10 yrs
Without any treatmment
次要结局
未报告次要终点
研究者
Paivi Halonen
Medical Oncologist
Helsinki University Central Hospital