a. Reducing Radioiodine Treatment in Papillary Thyroid Cancer. RAILESS

Not Applicable

Active, not recruiting

• Conditions: to Omit Radioiodine Treatment Safely in Patients With Low -Risk Papillary Thyroid Cancer With Seize of 11-20mm
• Interventions: Other: With radioiodine treatment; Procedure: With postoperative radioiodine treatment

• Registration Number: NCT06271044
• Lead Sponsor: Helsinki University Central Hospital

Brief Summary

To study if its is safe to reduce the amount of postoperative treatments in those patients, who have been operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level.

Detailed Description

The purpose of the study : to enroll about 50 patients operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level.

Methods: either to follow-up patients according to the study protocol without radioiodine treatment or to give a radioiodine treatment with a dose of 1.1 GBq according to the normal Finnish treatment protocol for papillary thyroid cancer to those patients who themselves preferred to have a normal postoperative treatment.

Study Timeline

• Study Start: 2014-10
• Status Verified: 2024-02
• Study First Submitted: 2024-02-14
• Study First Submitted QC: 2024-02-14
• Last Update Submitted: 2024-02-14
• Study First Posted: 2024-02-21
• Last Update Posted: 2024-02-21
• Primary Completion: 2024-12
• Study Completion: 2027-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 61

Inclusion Criteria

• low risk papillary intrathyroidal thyroid cancer with diameter of 11-20mm
• no lymphnode metastases

Exclusion Criteria

• high risk papillary cancer
• mutlifocal papillary cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
rairinn	With radioiodine treatment	THose patients receiving radioiodine treatment according to the normal treatment practice at that time
rairinn	With postoperative radioiodine treatment	THose patients receiving radioiodine treatment according to the normal treatment practice at that time

Primary Outcome Measures

Name	Time	Method
Event free situation during follow-up event free /disease free	10 yrs	Without any treatmment