Comparison of Maternal Neonatal Outcomes of Normotensive and Hypertensive Placental Abruptions: A Novel Approach
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Abruptio Placentae; Affecting Fetus or Newborn
- Sponsor
- Hatice Akkaya
- Enrollment
- 115
- Primary Endpoint
- blood pressure measurement
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process. Therefore, it is very important to understand these processes. To analyze maternal and neonatal effects of placental abruption(PA) through a novel classification in the presence of hypertension. Initial hemoglobin parameters were also compared to predict pregnancy outcomes in addition to hypertension.
Detailed Description
Objective: We aimed to classify placental abruption according to hypertension status. Methods: This retrospective cohort designed study was conducted on 115 pregnant women with placental abruption. The main parameters scanned and recorded from the hospital database and patient medical files. Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive). Maternal demographical and clinical characteristics (abdominal pain, vaginal bleeding) were recorded. APGAR scores below 5 at 1 and 5 min., fetal or neonatal death, admission and length of stay in Neonatal Intensive Care Unit(NICU) were also investigated and compared between the groups.
Investigators
Hatice Akkaya
Associate Professor
Kayseri Education and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •spontaneous,
- •singleton pregnancies
- •above 25 weeks of gestations with positive fetal cardiac activity
Exclusion Criteria
- •multiple gestations,
- •presence of fetal or maternal infection,
- •chronic inflammatory diseases or connective tissue disorders
- •history of myocardial infarction,
- •thrombosis
- •history of steroid drug usage.
Outcomes
Primary Outcomes
blood pressure measurement
Time Frame: 2 minute
mm Hg
Secondary Outcomes
- maternal and newborn length, weight(5 minute)
- hemogram parameters WBC(white blood cell) ,PLT(Platelet), MPV(mean platelet volume), HGB(hemoglobin), Neutrophil lymphocyte ratio..)(first 1 hour)
- APGAR score(5 minute)