Comparison of Maternal Neonatal Outcomes of Normotensive and Hypertensive Placental Abruptions: A Novel Approach
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 115
- 主要终点
- blood pressure measurement
研究概览
简要总结
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process. Therefore, it is very important to understand these processes. To analyze maternal and neonatal effects of placental abruption(PA) through a novel classification in the presence of hypertension. Initial hemoglobin parameters were also compared to predict pregnancy outcomes in addition to hypertension.
详细描述
Objective
We aimed to classify placental abruption according to hypertension status.
Methods: This retrospective cohort designed study was conducted on 115 pregnant women with placental abruption. The main parameters scanned and recorded from the hospital database and patient medical files. Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive). Maternal demographical and clinical characteristics (abdominal pain, vaginal bleeding) were recorded. APGAR scores below 5 at 1 and 5 min., fetal or neonatal death, admission and length of stay in Neonatal Intensive Care Unit(NICU) were also investigated and compared between the groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •spontaneous,
- •singleton pregnancies
- •above 25 weeks of gestations with positive fetal cardiac activity
排除标准
- •multiple gestations,
- •presence of fetal or maternal infection,
- •chronic inflammatory diseases or connective tissue disorders
- •history of myocardial infarction,
- •thrombosis
- •history of steroid drug usage.
结局指标
主要结局
blood pressure measurement
时间窗: 2 minute
mm Hg
次要结局
- maternal and newborn length, weight(5 minute)
- hemogram parameters WBC(white blood cell) ,PLT(Platelet), MPV(mean platelet volume), HGB(hemoglobin), Neutrophil lymphocyte ratio..)(first 1 hour)
- APGAR score(5 minute)
研究者
Hatice Akkaya
Associate Professor
Kayseri Education and Research Hospital