MedPath

A clinical trial to study the safety and efficacy of Peanut Safe Syringe

Phase 4
Completed
Conditions
Subjects of age between 18 to 50.For whom the Investigator considers that the compliance will be correct.
Registration Number
CTRI/2016/02/006638
Lead Sponsor
MERADAS
Brief Summary

This study is **‘A****randomized,controlled, single centre clinical study  to assess the safety &efficacy of Peanut Safe Syringe against the conventional syringes.’** Two groups willbe randomized for this study. One group will be using Peanut safe syringe andanother group will be using conventional syringe.In this study we will beassessing the safety & efficacy of **Peanut safe syringe** withthe help of questionnaires & QOL given to subjects and healthcareprofessionals separately.

- **Primary Objective-** To find out the efficacy of **Peanut safe syringe**, when compared with the conventional syringe available in the market

- **Secondary objective:** To assess the safety of **Peanut safe syringe**, , when compared with the conventional syringe available in the market

**Preclinicalexperience:**

A preclinical studyto assess the pain and behavioural changes in animals while using theinvestigational product were done in rabbits at the animal test facility atRadiant Research, Bangalore. The pain, behavioral and dermal activity inrabbits  were observed and scored by the investigational product incomparison with the control product (market product). Pain and behavioralscoring was done on the use of investigational product, whereas, dermalactivity was observed for 24 hour from the time of investigational product use.

The investigationalproduct, on usage didn’t cause any additional pain and behavioural changes inrabbits in comparison with control group  It was observed that, itdidn’t caused any additional dermal activity post usage up to 24 hrs.

**Clinical Trial Result**

This study was designed to explore thesafety, tolerability, and efficacy of Peanut Safe syringe.

Two hundred (200) adult subjects wereenrolled in the study and were randomize in two groups: Test & Control. Allthe subjects completed all the visits.

It can be concluded from this studythat Peanut safe syringe  is efficacious to be used in human subjects,

Analysis of safety parameters shows that investigationalproduct is not altering or causing any symptomatic reactions in subject’s safetyvariable.

It was found that Peanut safesyringe is safe for using in human subjects.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
200
Inclusion Criteria
  • aSubjects of age between 18 to 50.
  • bFor whom the Investigator considers that the compliance will be correct.
  • cCooperating, informed of the need and duration of the study, and ready to comply with protocol procedures.
  • dHaving signed a Consent Form and will be once informed orally and in writing of all information concerning the study procedures and study objectives.
Exclusion Criteria
  • a.Volunteers with any cardiac abnormalities or ailments or abnormal blood pressure.
  • b.Known sensitivity to the investigational product.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To find out the efficacy of Peanut safe syringeVisit 3
Secondary Outcome Measures
NameTimeMethod
To find the safety of Peanut safe syringeVisit 3

Trial Locations

Locations (1)

Mysore Medical College

🇮🇳

Mysore, KARNATAKA, India

Mysore Medical College
🇮🇳Mysore, KARNATAKA, India
Dr Bharathi Muniyappa
Principal investigator
9900397241
govt.k.r.hospital@gmail.com

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