NCT03163680已完成不适用
Efficacy of Low Dose of Proton Pumb Inhabitor in Treatment Upper Gastrointestinal Bleeding
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 295
- 试验地点
- 1
- 主要终点
- Morality
研究概览
简要总结
Determining the efficacy of low dose of PPI in management acute peptic ulcer bleeding
详细描述
Determining the efficacy of low dose meaning 40 mg of omeprazole twice in management acute peptic ulcer bleeding
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •High risk ulcers defined according to the Forrest classification With respect to high-risk stigmata, active bleeding was defined as a continuous blood spurting (Forrest IA) oozing (Forrest IB) from the ulcer base. A non-bleeding visible vessel at endoscopy was defined as a discrete protuberance at the ulcer base(Forrest IIA).
- •An adherent clot was one that was resistant to forceful irrigation or suction (Forrest IIB).
排除标准
- •ulcer was malignant non ulcerative bleeding such as angiodysplasia , a Mallory-Weiss tear
研究组 & 干预措施
Low Dose PPI
patients with upper upper gastrointestinal bleeding were treated in low dose of proton Bump inhibitor meaning 40 mg twice daily
干预措施: Omeprazole 40 MG (Drug)
结局指标
主要结局
Morality
时间窗: within 1 week
Determination of mortality rate from ulcer bleeding
次要结局
- Rebleeding(within 1 week)
- Length of hospital stay(within 1 month)
- need for surgery(within 1 week)
- Blood transfusions(within 1 week)
研究者
研究点 (1)
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