A Pilot Study to Evaluate Ultrasonic Surgical Aspiration as a Treatment Modality for Cervical Dysplasia
- Conditions
- Cervical Dysplasia
- Registration Number
- NCT00374114
- Lead Sponsor
- University of Tennessee
- Brief Summary
Ultrasonic surgical aspiration of the cervix may be an effective method of treating cervical dysplasia without compromising the integrity of the cervix in reproductive age women.
- Detailed Description
Women age 18 to 55 years of age with Cervical Intraepithelial Neoplasia 2 or 3 on colposcopy with a negative EndoCervical Curettage are enrolled in a pilot study comparing ultrasonic surgical aspiration and traditional cervical excision procedure for the treatment of cervical dysplasia. In this pilot study, the patients serve as their own control group. Prior to receiving the traditional treatment for cervical dysplasia consisting of Cold Knife Conization with EndoCervical Curettage, each patient's cervix is treated with ultrasonic surgical aspiration. The aspirate is sent to pathology and the results compared with the findings from the cervical cone biopsy. The patients then are followed with Liquid-based Cytology pap smears every 4 to 6 months until completion of the study enrollment/treatment period.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 20
- cervical intraepithelial neoplasia II or III
- negative endocervical curettage
- not pregnant
- cervical conization is part of treatment plan
- positive endocervical curettage
- pregnant
- medically unable to undergo surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Adequate treatment of cervical dysplasia
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
University of Tennessee Health Sciences Center
🇺🇸Memphis, Tennessee, United States
University of Tennessee College of Medicine
🇺🇸Chattanooga, Tennessee, United States